The City of Vancouver has received 176 applications for medical marijuana businesses under the new bylaws.
The city says 69 want to be licensed as compassion clubs, while the rest have applied as retail businesses.
The new regulations require dispensaries to keep a certain distance between themselves and other dispensaries, as well as from schools.
A business licence also costs $30,000, while it costs $1,000 for compassion clubs.
The City of Vancouver moved to regulate the illegal businesses because so many were popping up all over the city.
The drew criticism from the federal government.